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Article

SENP1 participates in Irinotecan resistance in human colon cancer cells

26 May 2021

Abstract excerpt

Abstract Colorectal cancer is one of the most prevalent cancers in the world. Chemoresistance has always been a problem encountered in its treatment. It is known that SUMOylation may regulate protein stability and decomposition, and even affect the protein translocation and posttranslational modification in cells. Sentrin‐specific protease 1 (SENP1) is involved in the maturation of SUMO protein, and on the other...

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PMID: 34037277
DOI: 10.1002/jcb.29946

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