Article
Chimerism monitoring using biallelic single nucleotide or insertion/deletion polymorphisms: How many markers to screen?
Clinica chimica acta; international journal of clinical chemistry - 1 Jul 2022
Vynck Matthijs, Nollet Friedel, Sibbens Lode, Devos Helena
Abstract excerpt
BACKGROUND/AIMS: Chimerism monitoring by means of high-throughput sequencing or quantitative PCR of biallelic single nucleotide and insertion/deletion polymorphisms has shown potential for improved patient care when compared to the gold standard capillary electrophoresis assays. When designing chimerism assays the number of markers to screen needs consideration: it determines the informativity rate and accuracy...
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