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Article

Genetically predicted vitamin K levels and risk of osteoarthritis: Mendelian randomization study.

Seminars in arthritis and rheumatism - 1 Aug 2022

Zhao Sizheng Steven, Bovijn Jonas, Hughes David M, Sha Tinting, Zeng Chao, Lyu Houchen

Abstract excerpt

OBJECTIVE: Osteoarthritis (OA) is a progressive disease for which there is no disease modifying therapy. Vitamin K levels and vitamin K antagonism have been associated with risk and progression of OA which may have direct implications for clinical management, but these observational findings are susceptible to confounding. We aimed to estimate the causal association between vitamin K and OA risk using Mendelian...

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Biotin and Related Studies
Genome-Wide Association Study
Mendelian Randomization Analysis
Osteoarthritis
Parathyroid Disorders and Treatments

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymorphism, Single Nucleotide

Vitamin K Research Studies

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PMID: 35667331
DOI: 10.1016/j.semarthrit.2022.152030

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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