Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

TRIB1 regulates tumor growth via controlling tumor-associated macrophage phenotypes and is associated with breast cancer survival and treatment response.

Theranostics - 1 Jan 2022

Kim Taewoo, Johnston Jessica, Castillo-Lluva Sonia, Cimas Francisco J, Hamby Stephen, Gonzalez-Moreno Santiago, Villarejo-Campos Pedro, Goodall Alison H, Velasco Guillermo, Ocana Alberto, Muthana Munitta, Kiss-Toth Endre

Abstract excerpt

Molecular mechanisms that regulate tumor-associated macrophage (TAM) phenotype and function are incompletely understood. The pseudokinase TRIB1 has been reported as a regulator of macrophage phenotypes, both in mouse and human systems. Methods: Bioinformatic analysis was used to investigate the link between TRIB1 expression in breast cancer and therapeutic response to chemotherapy. In vivo models of breast cancer...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Breast Neoplasms
Share to Cytokines

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Interleukin-15

Share to Intracellular Signaling Peptides and Proteins

Share to Phenotype

Share to Protein Serine-Threonine Kinases

Share to Tumor-Associated Macrophages

Source

Open in PubMed Open full text

Identifiers

PMID: 35664073
DOI: 10.7150/thno.72192
PMCID: PMC9131267

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

TRIB1 regulates tumor growth via controlling tumor-associated macrophage phenotypes and is associated with breast cancer survival and treatment response.PMID 35664073Read ↗

TRIB1 regulates tumour growth via controlling tumour-associated macrophage phenotypes and is associated with breast cancer survival and treatment responseSemantic proximity Read ↗

TRIB1 modulates transcriptional programming in breast cancer cells to regulate cell proliferationSemantic proximity Read ↗

Tribbles-1 Expression and Its Function to Control Inflammatory Cytokines, Including Interleukin-8 Levels are Regulated by miRNAs in Macrophages and Prostate Cancer Cells.Semantic proximity Read ↗

Comprehensive pan-cancer analysis unveils the significant prognostic value and potential role in immune microenvironment modulation of TRIB3Semantic proximity Read ↗

Critical role of Trib1 in differentiation of tissue-resident M2-like macrophagesSemantic proximity Read ↗

An iron-rich subset of macrophages promotes tumor growth through a Bach1-Ednrb axisSemantic proximity Read ↗

Understanding tissue-resident macrophages unlocks the potential for novel combinatorial strategies in breast cancerSemantic proximity Read ↗

The cellular and molecular origin of tumor-associated macrophagesSemantic proximity Read ↗

TFEB is a master regulator of tumor-associated macrophages in breast cancerSemantic proximity Read ↗

TREM2 blockade reprograms HER2 CAR macrophages toward inflammatory phagocytes in breast cancer modelsSemantic proximity Read ↗

TRIB3 promotes MYC-associated lymphoma development through suppression of UBE3B-mediated MYC degradationSemantic proximity Read ↗

Involvement of protumor macrophages in breast cancer progression and characterization of macrophage phenotypes.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.