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Article

Association of emergence of new mutations in circulating tumuor DNA during chemotherapy with clinical outcome in metastatic colorectal cancer.

BMC cancer - 22 Jul 2021

Jia Ning, Chang Lianpeng, Gao Xin, Shi Xiaohua, Dou Xuelin, Guan Mei, Shao Yajuan, Li Ningning, Cheng Yuejuan, Ying Hongyan, Sun Zhao, Zhou Yanping, Zhao Lin, Zhou Jianfeng, Bai Chunmei

Abstract excerpt

BACKGROUND: The understanding of molecular changes in mCRC during treatment could be used to personalise therapeutic strategies. The aim of our study was to explore the association of circulating tumour DNA (ctDNA) with clinical outcome in metastatic colorectal cancer (mCRC). METHODS: Sequential patients with mCRC receiving standard first-line chemotherapy were included prospectively. Both plasma ctDNA and serum...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 34294055
DOI: 10.1186/s12885-021-08309-2
PMCID: PMC8296534

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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