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Monitoring and adapting cancer treatment using circulating tumor DNA kinetics: Current research, opportunities, and challenges

26 Jan 2022

Abstract excerpt

Circulating tumor DNA (ctDNA) has emerged as a biomarker with wide-ranging applications in cancer management. While its role in guiding precision medicine in certain tumors via noninvasive detection of susceptibility and resistance alterations is now well established, recent evidence has pointed to more generalizable use in treatment monitoring. Quantitative changes in ctDNA levels over time (i.e., ctDNA...

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PMID: 35080978
DOI: 10.1126/sciadv.abi8618

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