Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Impaired renal transporter gene expression and uremic toxin excretion as aging hallmarks in cats with naturally occurring chronic kidney disease

20 Dec 2024

Abstract excerpt

Aging leads to nephron senescence and chronic kidney disease (CKD). In cats, indoxyl sulfate (IxS) has been previously quantified and associated with CKD, and little is known about tubular transporters. Two cohorts of cats aged 6 to 21 years were enrolled. Cohort 1 included 41 colony cats with 28 control and 13 CKD cats. Cohort 2 had 30 privately-owned cats with 10 control and 20 CKD cats. In cohort 1, serum...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Dialysis and Renal Disease Management
Share to Diet and metabolism studies
Share to Electrolyte and hormonal disorders

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 39729035
DOI: 10.18632/aging.206176

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Impaired renal transporter gene expression and uremic toxin excretion as aging hallmarks in cats with naturally occurring chronic kidney diseasePMID 39729035Read ↗

Handling of Drugs, Metabolites, and Uremic Toxins by Kidney Proximal Tubule Drug TransportersSemantic proximity Read ↗

Protein-Bound Uremic Toxins in Senescence and Kidney FibrosisSemantic proximity Read ↗

Chronic Kidney Disease in Dogs and CatsSemantic proximity Read ↗

Metabolomic Changes Associated with AGXT2 Genotype Variants and Stone Formation in a Colony of Cats.Semantic proximity Read ↗

Characterization of Kidney Injury Molecule-1 in CatsSemantic proximity Read ↗

Mammalian urea transportersSemantic proximity Read ↗

Uremic Toxin-Producing Gut Microbiota in Rats with Chronic Kidney DiseaseSemantic proximity Read ↗

The Impact of Uremia and Intestinal Dysbiosis on Hepatic Drug Metabolism in a Rat Model of Progressive Chronic Kidney DiseaseSemantic proximity Read ↗

Assessment of Human Renal Transporter Based Drug-Drug Interactions Using Proximal Tubule Kidney-ChipSemantic proximity Read ↗

First genome-wide association study investigating blood pressure and renal traits in domestic cats.Semantic proximity Read ↗

Rapid Recovery of Male Cats with Postrenal Acute Kidney Injury by Treating with Allogeneic Adipose Mesenchymal Stem Cell-derived ExosomesSemantic proximity Read ↗

Apoptosis Inhibitor of Macrophages in Cats: A Potential Link Between an Exon 3 Variant Allele and Progression of Naturally Occurring Chronic Kidney DiseaseSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.