Article
Current status of beta-thalassemia and its treatment strategies.
Molecular genetics & genomic medicine - 1 Dec 2021
Ali Shaukat, Mumtaz Shumaila, Shakir Hafiz Abdullah, Khan Muhammad, Tahir Hafiz Muhammad, Mumtaz Samaira, Mughal Tafail Akbar, Hassan Ali, Kazmi Syed Akif Raza, Sadia, Irfan Muhammad, Khan Muhammad Adeeb
Abstract excerpt
BACKGROUND: Thalassemia is an inherited hematological disorder categorized by a decrease or absence of one or more of the globin chains synthesis. Beta-thalassemia is caused by one or more mutations in the beta-globin gene. The absence or reduced amount of beta-globin chains causes ineffective erythropoiesis which leads to anemia. METHODS: Beta-thalassemia has been further divided into three main forms:...
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