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Alz-Disc: A Tool to Discriminate Disease-causing and Neutral Mutations in Alzheimer's Disease.

Combinatorial chemistry & high throughput screening - 1 Jan 2023

Kulandaisamy A, Parvathy Dharshini S Akila, Gromiha M Michael

Abstract excerpt

BACKGROUND: Alzheimer's disease (AD) is the most common neurodegenerative disorder that affects the neuronal system and leads to memory loss. Many coding gene variants are associated with this disease and it is important to characterize their annotations. METHODS: We collected the Alzheimer's disease-causing and neutral mutations from different databases. For each mutation, we computed the different features from...

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PMID: 35619290
DOI: 10.2174/1386207325666220520102316

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