Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mendelian Randomization: Principles and its usage in Lp(a) research.

Atherosclerosis - 1 May 2022

Lamina Claudia

Abstract excerpt

Epidemiological studies investigating the association between a biomarker and a disease have many limitations. The most prominent among these is that we cannot impute causality purely from a statistical association. If we observe an association, the biomarker might really be causal for the development of the disease, the association might be caused by a confounding variable or by reverse causation. With Mendelian...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Apolipoproteins A
Share to Apoprotein(a)
Share to Biomarkers

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genome-Wide Association Study

Share to Lipoprotein(a)

Share to Lymphoma Diagnosis and Treatment

Share to Mendelian Randomization Analysis

Share to Polymorphism, Single Nucleotide

Source

Identifiers

PMID: 35606074
DOI: 10.1016/j.atherosclerosis.2022.04.013

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mendelian Randomization: Principles and its usage in Lp(a) research.PMID 35606074Read ↗

Lipoprotein(a): from Causality to Treatment.Semantic proximity Read ↗

Human Genetics and the Causal Role of Lipoprotein(a) for Various Diseases.Semantic proximity Read ↗

Lipoprotein (a) as a cause of cardiovascular disease: insights from epidemiology, genetics, and biology.Semantic proximity Read ↗

From genome-wide association studies to Mendelian randomization: novel opportunities for understanding cardiovascular disease causality, pathogenesis, prevention, and treatment.Semantic proximity Read ↗

Proteomic Insights into Lp(a) Cardiovascular Mechanisms: A Mendelian Randomization StudySemantic proximity Read ↗

Mendelian randomization studies in coronary artery disease.Semantic proximity Read ↗

Mendelian randomization for cardiovascular diseases: principles and applicationsSemantic proximity Read ↗

Mendelian Randomization Analysis as a Tool to Gain Insights into Causes of Diseases: A Primer.Semantic proximity Read ↗

Evaluating genetically-predicted causal effects of lipoprotein(a) in human diseases: a phenome-wide Mendelian randomization studySemantic proximity Read ↗

Association of LPA Variants With Risk of Coronary Disease and the Implications for Lipoprotein(a)-Lowering Therapies: A Mendelian Randomization Analysis.Semantic proximity Read ↗

The relationship between lipoprotein(a) and risk of cardiovascular disease: a Mendelian randomization analysis.Semantic proximity Read ↗

Prediction of cardiovascular risk by Lp(a) concentrations or genetic variants within the LPA gene regionSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.