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Article

HLA-B15:11 status and carbamazepine-induced severe cutaneous adverse drug reactions in HLA-B15:02 negative Chinese.

International journal of dermatology - 1 Feb 2022

Wong Christina S M, Yap Desmond Y H, Ip Patrick, Wong Wilfred H S, Chua Gilbert T, Yeung Chi-Keung, Chan Henry H L, Kwok Janette S Y

Abstract excerpt

BACKGROUND: HLA-B*15:11 is associated with carbamazepine (CBZ)-induced severe cutaneous adverse drug reactions (SCARs) in Japanese and some Asian populations, but such data remains relatively limited in Chinese. Routine HLA-B*15:02 screening is mandatory before CBZ commencement, however, SCARs related to CBZ were still observed in non-HLA*B-15:02 carriers. OBJECTIVE: We aimed to find out the prevalence of...

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Anticonvulsants
Carbamazepine
China
Genetic Predisposition to Disease
HLA-B Antigens

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

HLA-B15 Antigen

Stevens-Johnson Syndrome

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PMID: 34553372
DOI: 10.1111/ijd.15792

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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