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Article

The potential impact of CYP2D6 (2/4/*10) gene variants among Egyptian epileptic children: A preliminary study.

Gene - 20 Jul 2022

Elsaid Afaf M, Zahran Rasha F, Elmetwaly Samar M, Wahba Yahya, Megahed Hisham, Elshazli Rami M

Abstract excerpt

BACKGROUND: The cytochrome P450 (CYP) isoenzymes have an indispensable role in the metabolic phase of different medications during the treatment of multiple neuropsychiatric disorders. The foremost goal of this study is to evaluate the correlation of the allelic variants within CYP2D6 (*2/*4/*10) gene with the susceptibility for epileptic syndrome as well as the assessment the degree of resistance towards...

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PMID: 35597526
DOI: 10.1016/j.gene.2022.146585

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