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Germline pathogenic variants identification through Comprehensive Cancer Genome Profiling

2025-12-08

Abstract excerpt

<title>Abstract</title> <p> <bold>Background:</bold> Comprehensive cancer genome profiling (CGP) is recommended for the identification of actionable somatic mutations in a selected subgroup of cancer patients. Some variants detected by CGP can be constitutional. The aim of this study is to evaluate the rate of potential and confirmed constitutional pathogenic/likely pathogenic variants (overall defined as PVs)...

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Literature Corpus work
cf894916-f8d3-5c3e-8583-e0b887b69e0b
DOI
10.21203/rs.3.rs-8088663/v1
Open publication

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Germline pathogenic variants identification through Comprehensive Cancer Genome ProfilingDOI 10.21203/rs.3.rs-8088663/v1
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