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Article

Frequency of actionable germline pathogenic variants identified through tumor next-generation sequencing in a gynecologic cancer cohort.

International journal of gynecological cancer : official journal of the International Gynecological Cancer Society - 3 Jul 2023

Karpel Hannah, Manderski Elizabeth, Pothuri Bhavana

Abstract excerpt

BACKGROUND: Tumor next-generation sequencing can identify potential germline pathogenic variants associated with cancer susceptibility. OBJECTIVE: To describe the frequency of tumor sequencing results that met European Society of Medical Oncology (ESMO) recommendations for further germline genetic testing, and the frequency of germline variants among a cohort with gynecologic cancer. METHODS: Patients with...

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Identifiers

PMID: 36889816
DOI: 10.1136/ijgc-2022-004142

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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