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Article

SORBS2 as a molecular target for atherosclerosis in patients with familial hypercholesterolemia

19 May 2022

Abstract excerpt

BACKGROUND: Familial hypercholesterolemia (FH) is a metabolic disease in which patients are prone to develop premature atherosclerosis (AS). Sorbin and SH3 Domain Containing 2 (SORBS2) is known to play a role in coronary heart disease (CHD). However, the mechanism underlying SORBS2 involvement in the development of hypercholesterolemia remains unknown. Here, we investigated the effects of SORBS2 on inflammation...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 35590369
DOI: 10.1186/s12967-022-03381-z

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