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Article

Investigation of the underlying genes and mechanism of familial hypercholesterolemia through bioinformatics analysis.

BMC cardiovascular disorders - 16 Sept 2020

Wang Dinghui, Liu Bin, Xiong Tianhua, Yu Wenlong, She Qiang

Abstract excerpt

BACKGROUND: Familial hypercholesterolemia (FH) is one of the commonest inherited metabolic disorders. Abnormally high level of low-density lipoprotein cholesterol (LDL-C) in blood leads to premature atherosclerosis onset and a high risk of cardiovascular disease (CVD). However, the specific mechanisms of the progression process are still unclear. Our study aimed to investigate the potential differently expressed...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32938406
DOI: 10.1186/s12872-020-01701-z
PMCID: PMC7493348

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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