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Article

Sestrin2: Its Potential Role and Regulatory Mechanism in Host Immune Response in Diseases

4 Dec 2019

Abstract excerpt

Sestrin2 (SESN2), a highly evolutionarily conserved protein, is critically involved in cellular responses to various stresses. SESN2 has a protective effect on physiological and pathological states mainly via regulating oxidative stress, endoplasmic reticulum stress, autophagy, metabolism, and inflammation. In recent years, breakthrough investigations with regard to the regulation and signaling mechanisms of...

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PMID: 31867002
DOI: 10.3389/fimmu.2019.02797

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