Article
Combined impacts of histamine receptor H1 gene polymorphisms and an environmental carcinogen on the susceptibility to and progression of oral squamous cell carcinoma.
Aging - 19 May 2022
Ding Yi-Fang, Lin Yung-Wei, Chiu Wen-Kuan, Lin Chiao-Wen, Yang Yi-Chieh, Chang Lun-Ching, Chang Jungshan, Yang Shun-Fa, Chien Ming-Hsien
Abstract excerpt
Oral squamous cell carcinoma (OSCC) is the most frequently encountered type of oral cancer. Histamine receptor H1 (HRH1) was reported to play a crucial role in OSCC carcinogenesis, but impacts of genetic variants of HRH1 on OSCC remain unclear. Herein, we investigated the association between functional single-nucleotide polymorphisms (SNPs) of HRH1 and OSCC susceptibility or clinicopathologic variables by...
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