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Article

Integrative genomic analyses of the histamine H1 receptor and its role in cancer prediction.

International journal of molecular medicine - 1 Apr 2014

Wang Minghai, Wei Xiaolong, Shi Lianghui, Chen Bin, Zhao Guohai, Yang Haiwei

Abstract excerpt

The human histamine receptor H1 (HRH1) gene is located on chromosome 3p25 and encodes for a 487 amino acid G protein-coupled receptor (GPCR) with a long third intracellular loop (IL3). The HRH1 predominantly couples to Gαq/11 proteins, leading to the activation of phospholipase C (PLC) and subsequent release of the second messengers inositol trisphosphate (IP3) and diacylglycerol (DAG) followed by the activation...

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Source

Identifiers

PMID: 24535227
DOI: 10.3892/ijmm.2014.1649

Genes

HRH1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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