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Article

Association between common genetic variant of HRH2 and gastric cancer risk.

International journal of oncology - 1 Aug 2012

Arisawa Tomiyasu, Tahara Tomomitsu, Ozaki Kazuaki, Matsue Yasuhiro, Minato Takahiro, Yamada Hideto, Nomura Tomoe, Hayashi Ranji, Matsunaga Kazuhiro, Fukumura Atsushi, Nakamura Masakatsu, Toshikuni Nobuyuki, Shiroeda Hisakazu, Shibata Tomoyuki

Abstract excerpt

Histamine plays important physiological roles in the upper gastrointestinal tract and acts via the H2 receptor. The -1018 G>A (rs2067474) in an enhancer element of the promoter and non-synonymous rs79385261 (Asn46Thr) were identified in HRH2. We attempted to clarify the associations of these polymorphisms with gastric carcinogenesis. The study was performed in 321...

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Identifiers

PMID: 22615049
DOI: 10.3892/ijo.2012.1482

Genes

HRH2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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