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Article

Resistance to cis- and carboplatin initiated by epigenetic changes in ovarian cancer patients

1 Jan 2019

Abstract excerpt

Initially, most ovarian tumors respond to the treatment with platinum components, but frequently recurrence occurs within the following two years in advanced ovarian cancer patients. In this regard, previous studies have shown changes in the epigenetic patterns in ovarian cancer that are linked with resistance to cis- and carboplatin therapy. Thus, epigenetic changes mediated by a treatment with cis- or...

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Share to Chemotherapy-induced organ toxicity mitigation
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Identifiers

PMID: 35582723
DOI: 10.20517/cdr.2019.010

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