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Article

Body composition is associated with tacrolimus pharmacokinetics in kidney transplant recipients.

European journal of clinical pharmacology - 1 Aug 2022

Francke M I, Visser W J, Severs D, de Mik-van Egmond A M E, Hesselink D A, De Winter B C M

Abstract excerpt

PURPOSE: A population pharmacokinetic (popPK) model may be used to improve tacrolimus dosing and minimize under- and overexposure in kidney transplant recipients. It is unknown how body composition parameters relate to tacrolimus pharmacokinetics and which parameter correlates best with tacrolimus exposure. The aims of this study were to investigate which body composition parameter has the best association with...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 35567629
DOI: 10.1007/s00228-022-03323-0
PMCID: PMC9283366

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