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Regulation of NKG2D Stress Ligands and Its Relevance in Cancer Progression

9 May 2022

Abstract excerpt

Under cellular distress, multiple facets of normal homeostatic signaling are altered or disrupted. In the context of the immune landscape, external and internal stressors normally promote the expression of natural killer group 2 member D (NKG2D) ligands that allow for the targeted recognition and killing of cells by NKG2D receptor-bearing effector populations. The presence or absence of NKG2D ligands can heavily...

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CAR-T cell therapy research
Immune Cell Function and Interaction
T-cell and B-cell Immunology

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 35565467
DOI: 10.3390/cancers14092339

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