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Article

Effect of NKG2D ligand expression on host immune responses

28 Apr 2010

Abstract excerpt

Natural killer group 2, member D (NKG2D) is an activating receptor present on the surface of natural killer (NK) cells, some NKT cells, CD8(+) cytotoxic T cells, gammadelta T cells, and under certain conditions CD4(+) T cells. Present in both humans and mice, this highly conserved receptor binds to a surprisingly diverse family of ligands that are distant relatives of major histocompatibility complex class I...

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PMID: 20536569
DOI: 10.1111/j.0105-2896.2010.00893.x

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