Experience of risk-reducing salpingo-oophorectomy for a BRCA1 mutation carrier and establishment of a system performing a preventive surgery for hereditary breast and ovarian cancer syndrome in Japan: our challenges for the future.

doi:10.1093/jjco/hyt036

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Experience of risk-reducing salpingo-oophorectomy for a BRCA1 mutation carrier and establishment of a system performing a preventive surgery for hereditary breast and ovarian cancer syndrome in Japan: our challenges for the future.

Japanese journal of clinical oncology - 1 May 2013

Hirasawa Akira, Masuda Kenta, Akahane Tomoko, Tsuruta Tomohiko, Banno Kouji, Makita Kazuya, Susumu Nobuyuki, Jinno Hiromitsu, Kitagawa Yuko, Sugano Kokichi, Kosaki Kenjiro, Aoki Daisuke

Abstract excerpt

BACKGROUND: Risk-reducing salpingo-oophorectomy is currently regarded as the most certain primary method for preventing ovarian cancer among BRCA1/2 mutation carriers with hereditary breast and ovarian cancer syndrome. However, risk-reducing salpingo-oophorectomy has rarely been performed in Japan. METHODS: We developed the first system in Japan for performing risk-reducing salpingo-oophorectomy for BRCA1/2...

Topics

Adult
BRCA1 Protein
BRCA2 Protein
Breast Neoplasms
Female
Genetic Counseling
Genetic Predisposition to Disease
Genetic Testing
Hereditary Breast and Ovarian Cancer Syndrome

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Heterozygote

Humans

Insurance Coverage

Japan

Middle Aged

Mutation

Ovarian Neoplasms

Ovariectomy

Pedigree

Source

Open in PubMed

Identifiers

PMID: 23487443
DOI: 10.1093/jjco/hyt036

Genes

BRCA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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Experience of risk-reducing salpingo-oophorectomy for a BRCA1 mutation carrier and establishment of a system performing a preventive surgery for hereditary breast and ovarian cancer syndrome in Japan: our challenges for the future.PMID 23487443Read ↗

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