Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Docosahexaenoic acid may inhibit immune evasion of colorectal cancer cells through targeting immune checkpoint and immunomodulator genes and their controlling microRNAs

9 May 2022

Abstract excerpt

Colorectal cancer is one of the major concerns in both developed and developing societies. Because of the serious side effects of the current treatments, novel therapy agents have been developed that target immune checkpoint and immunomodulatory molecules in the tumor environment. Therefore, this study investigates the effect of docosahexaenoic acid (DHA) fatty acid on the expression of immune checkpoint...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer, Lipids, and Metabolism
Share to Cancer, Stress, Anesthesia, and Immune Response
Share to Immune cells in cancer

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 35533068
DOI: 10.1002/biof.1842

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Docosahexaenoic acid may inhibit immune evasion of colorectal cancer cells through targeting immune checkpoint and immunomodulator genes and their controlling microRNAsPMID 35533068Read ↗

Docosahexaenoic Acid Induces Oxidative DNA Damage and Apoptosis, and Enhances the Chemosensitivity of Cancer CellsSemantic proximity Read ↗

Smad7 is a negative regulator of immunogenic cell death in colorectal cancerSemantic proximity Read ↗

Transcriptomics Reveals the Mevalonate and Cholesterol Pathways Blocking as Part of the Bacterial Cyclodipeptides Cytotoxic Effects in HeLa Cells of Human Cervix AdenocarcinomaSemantic proximity Read ↗

Colorectal ALOX15 as a host factor determinant of EPA and DHA effects on colorectal carcinogenesisSemantic proximity Read ↗

Expression of the membrane complement regulatory protein CD59 (protectin) is associated with reduced survival in colorectal cancer patientsSemantic proximity Read ↗

Bile acids destabilise HIF-1α and promote anti-tumour phenotypes in cancer cell models.Semantic proximity Read ↗

GRIM‐19 repressed hypoxia‐induced invasion and EMT of colorectal cancer by repressing autophagy through inactivation of STAT3/HIF‐1α signaling axisSemantic proximity Read ↗

Zebularine inhibits tumorigenesis and stemness of colorectal cancer via p53-dependent endoplasmic reticulum stressSemantic proximity Read ↗

Omega-3 fatty acid is a potential preventive agent for recurrent colon cancer.Semantic proximity Read ↗

Loss of fatty acid synthase suppresses the malignant phenotype of colorectal cancer cells by down-regulating energy metabolism and mTOR signaling pathway.Semantic proximity Read ↗

The Safe Soluble Compound Dehydroascorbic Acid Inhibits Various Upstream and Downstream Effectors of PI3K and KRAS Signaling Pathways in Undruggable PIK3CA/KRAS-Mutant Colorectal Cancer Stem-Like Cells.Semantic proximity Read ↗

Omega-3 Fatty Acid DHA Induces Ferroptosis in Colorectal Cancer Patient-Derived Organoids and Drug-Tolerant CellsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.