Article
Suppression of Th17 cell differentiation via sphingosine-1-phosphate receptor 2 by cinnamaldehyde can ameliorate ulcerative colitis.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie - 1 Feb 2021
Qu Shu-Lan, Chen Long, Wen Xue-Shan, Zuo Jian-Ping, Wang Xiao-Yu, Lu Zhi-Jie, Yang Yi-Fu
Abstract excerpt
Ulcerative colitis (UC) is chronic disease characterized by diffuse inflammation of the mucosa of the colon and rectum. Although the etiology is unknown, dysregulation of the intestinal mucosal immune system is closely related to UC. Cinnamaldehyde (CA) is a major active compound from cinnamon, is known as its anti-inflammatory and antibacterial. However, little research focused on its regulatory function on...
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