Myeloma Genome Project Panel is a Comprehensive Targeted Genomics Panel for Molecular Profiling of Patients with Multiple Myeloma.

doi:10.1158/1078-0432.CCR-21-3695

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Myeloma Genome Project Panel is a Comprehensive Targeted Genomics Panel for Molecular Profiling of Patients with Multiple Myeloma.

Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Jul 2022

Sudha Parvathi, Ahsan Aarif, Ashby Cody, Kausar Tasneem, Khera Akhil, Kazeroun Mohammad H, Hsu Chih-Chao, Wang Lin, Fitzsimons Evelyn, Salminen Outi, Blaney Patrick, Czader Magdalena, Williams Jonathan, Abu Zaid Mohammad I, Ansari-Pour Naser, Yong Kwee L, van Rhee Frits, Pierceall William E, Morgan Gareth J, Flynt Erin, Gooding Sarah, Abonour Rafat, Ramasamy Karthik, Thakurta Anjan, Walker Brian A

Abstract excerpt

PURPOSE: We designed a comprehensive multiple myeloma targeted sequencing panel to identify common genomic abnormalities in a single assay and validated it against known standards. EXPERIMENTAL DESIGN: The panel comprised 228 genes/exons for mutations, 6 regions for translocations, and 56 regions for copy number abnormalities (CNA). Toward panel validation, targeted sequencing was conducted on 233 patient samples...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 35522533
DOI: 10.1158/1078-0432.CCR-21-3695
PMCID: PMC9250632

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