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Article

DMG26: A Targeted Sequencing Panel for Mutation Profiling to Address Gaps in the Prognostication of Multiple Myeloma.

The Journal of molecular diagnostics : JMD - 1 Dec 2021

Cutler Samuel D, Knopf Philipp, Campbell Clinton J V, Thoni Andrea, Abou El Hassan Mohamed, Forward Nicholas, White Darrell, Wagner Julie, Goudie Marissa, Boudreau Jeanette E, Kennedy Barry E, Gujar Shashi, Gaston Daniel, Elnenaei Manal O

Abstract excerpt

Multiple myeloma presents with numerous primary genomic lesions that broadly dichotomize cases into hyperdiploidy or IgH translocated. Clinically, these large alterations are assessed by fluorescence in situ hybridization (FISH) for risk stratification at diagnosis. Secondary focal events, including indels and single-nucleotide variants, are also reported; however, their clinical correlates are poorly described,...

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Share to Aged, 80 and over
Share to Cell Line, Tumor

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Copy Number Variations

Share to Gene Expression Regulation, Neoplastic

Share to In Situ Hybridization, Fluorescence

Share to Multiple Myeloma

Share to Prognosis

Share to Progression-Free Survival

Source

Identifiers

PMID: 34562616
DOI: 10.1016/j.jmoldx.2021.08.011

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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