Article
Immunogenetic clustering of 30 cancers.
Scientific reports - 4 May 2022
James Lisa M, Georgopoulos Apostolos P
Abstract excerpt
Human leukocyte antigen (HLA) genes have been implicated in cancer risk and shared heritability of different types of cancer. In this immunogenetic epidemiological study we first computed a Cancer-HLA profile for 30 cancer types characterized by the correlation between the prevalence of each cancer and the population frequency of 127 HLA alleles, and then used multidimensional scaling to evaluate the possible...
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