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Article

Association of HLA diversity with the risk of 25 cancers in the UK Biobank.

EBioMedicine - 1 Jun 2023

Wang Qiao-Ling, Wang Tong-Min, Deng Chang-Mi, Zhang Wen-Li, He Yong-Qiao, Xue Wen-Qiong, Liao Ying, Yang Da-Wei, Zheng Mei-Qi, Jia Wei-Hua

Abstract excerpt

BACKGROUND: The human leukocyte antigen (HLA) is a highly polymorphic region, and HLA diversity may play a role in presenting tumour-associated peptides and inducing immune responses. However, the effect of HLA diversity on cancers has not been fully assessed. We aimed to explore the role of HLA diversity on cancer development. METHODS: A pan-cancer analysis was performed to evaluate the effect of HLA diversity,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Predisposition to Disease

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Source

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Identifiers

PMID: 37148584
DOI: 10.1016/j.ebiom.2023.104588
PMCID: PMC10189092

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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