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Article

DNMT3B (rs2424913) polymorphism is associated with systemic lupus erythematosus alone and with co-existing periodontitis in a Brazilian population.

Journal of applied oral science : revista FOB - 1 Jan 2022

Dias Larissa Nadine da Silva, Coêlho Marina de Castro, Persuhn Darlene Camati, Ribeiro Isabella Lima Arrais, Freire Eutilia Andrade Medeiros, Oliveira Naila Francis Paulo de, Aquino Sabrina Garcia de

Abstract excerpt

The association between Periodontitis and Systemic Lupus Erythematosus (SLE) has been primarily based on their similar pathophysiology and both are associated with genetic polymorphisms. OBJECTIVES: To investigate an association between the methylation-related gene polymorphisms DNMT3B (rs2424913) and MTHFR (rs1801133) to Systemic Lupus Erythematosus (SLE) and Periodontitis. METHODOLOGY: In total, 196 individuals...

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PMID: 35507987
DOI: 10.1590/1678-7757-2021-0567
PMCID: PMC9064189

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