Article
The combined genotypes of stimulatory and inhibitory Fc gamma receptors associated with systemic lupus erythematosus and periodontitis in Japanese adults.
Journal of periodontology - 1 Mar 2007
Kobayashi Tetsuo, Ito Satoshi, Yasuda Keiko, Kuroda Takeshi, Yamamoto Kouji, Sugita Noriko, Tai Hideaki, Narita Ichiei, Gejyo Fumitake, Yoshie Hiromasa
Abstract excerpt
BACKGROUND: The pathobiology of systemic lupus erythematosus (SLE) is similar to that of periodontitis in that the immunoglobulin G Fc receptor (FcgammaR) and proinflammatory cytokines play an important role. Genetic variations of FcgammaR and interleukin (IL)-1 are associated with susceptibility to both diseases. Therefore, we evaluated whether the combination of FcgammaR or IL-1 polymorphic genes represents a...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
