Article
miR-9-1 gene methylation and DNMT3B (rs2424913) polymorphism may contribute to periodontitis.
Journal of applied oral science : revista FOB - 1 Jan 2020
Coêlho Marina Castro, Queiroz Ingrid Costa, Viana Filho José Maria Chagas, Aquino Sabrina Garcia de, Persuhn Darlene Camati, Oliveira Naila Francis Paulo de
Abstract excerpt
BACKGROUND: Genetic and epigenetic changes have been associated with periodontitis in various genes; however, little is known about genes involved in epigenetic mechanisms and in oxidative stress. OBJECTIVE: This study aims to investigate the association of polymorphisms C677T in MTHFR (rs1801133) and -149C→T in DNMT3B (rs2424913), as well as the methylation profiles of MTHFR, miR-9-1, miR-9-3, SOD1, and CAT with...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
