Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Alterations in SARS-CoV-2 Omicron and Delta peptides presentation by HLA molecules.

PeerJ - 1 Jan 2022

Nersisyan Stepan, Zhiyanov Anton, Zakharova Maria, Ishina Irina, Kurbatskaia Inna, Mamedov Azad, Galatenko Alexei, Shkurnikov Maxim, Gabibov Alexander, Tonevitsky Alexander

Abstract excerpt

The T-cell immune response is a major determinant of effective SARS-CoV-2 clearance. Here, using the recently developed T-CoV bioinformatics pipeline (https://t-cov.hse.ru) we analyzed the peculiarities of the viral peptide presentation for the Omicron, Delta and Wuhan variants of SARS-CoV-2. First, we showed the absence of significant differences in the presentation of SARS-CoV-2-derived peptides by the most...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to HLA-DRB1 Chains
Share to Alleles

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Antigen Presentation

Share to COVID-19

Share to Peptides

Share to SARS-CoV-2

Share to SARS-CoV-2 and COVID-19 Research

Share to vaccines and immunoinformatics approaches

Source

Open in PubMed Open full text

Identifiers

PMID: 35502206
DOI: 10.7717/peerj.13354
PMCID: PMC9055995

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Alterations in SARS-CoV-2 Omicron and Delta peptides presentation by HLA molecules.PMID 35502206Read ↗

T-CoV: a comprehensive portal of HLA-peptide interactions affected by SARS-CoV-2 mutations.Semantic proximity Read ↗

SARS-CoV-2 Omicron (BA.1 and BA.2) specific novel CD8+ and CD4+ T cell epitopes targeting spike proteinSemantic proximity Read ↗

Prediction of SARS-CoV2 spike protein epitopes reveals HLA-associated susceptibilitySemantic proximity Read ↗

The T cell epitope landscape of SARS-CoV-2 variants of concernSemantic proximity Read ↗

A bioinformatic analysis of T-cell epitope diversity in SARS-CoV-2 variants: association with COVID-19 clinical severity in the United States population.Semantic proximity Read ↗

Mutations in spike protein T cell epitopes of SARS-COV-2 variants: Plausible influence on vaccine efficacy.Semantic proximity Read ↗

Evasive Spike Variants Elucidate the Preservation of T Cell Immune Response to the SARS-CoV-2 Omicron Variant.Semantic proximity Read ↗

The ATLAS™ screening assay reveals distinct CD4 <sup>+</sup> and CD8 <sup>+</sup> SARS-CoV-2 antigen response profiles which have implications to Omicron cellular immunitySemantic proximity Read ↗

CD8+ T Cell Epitope Variations Suggest a Potential Antigen Presentation Deficiency for Spike Protein of SARS-CoV-2Semantic proximity Read ↗

Predicted HLA Class I and Class II Epitopes From Licensed Vaccines Are Largely Conserved in New SARS-CoV-2 Omicron Variant of Concern.Semantic proximity Read ↗

HLA variants and TCR diversity against SARS-CoV-2 in the pre-COVID-19 era.Semantic proximity Read ↗

SARS-CoV-2 Spike Protein-Derived Immunogenic Peptides that are Promiscuously Presented by Several HLA-Class II Molecules and Their Potential for Inducing Acquired ImmunitySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.