The Role of HLA-DRB1 Alleles in Pulmonary Cystic Fibrosis.

doi:10.18502/ijaai.v21i2.9226

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Article

The Role of HLA-DRB1 Alleles in Pulmonary Cystic Fibrosis.

Iranian journal of allergy, asthma, and immunology - 11 Apr 2022

Asef Alireza, Ghafaripour Hossein Ali, Jamaati Hamidreza, Varahram Mohammad, M Adcock Ian, Mortaz Esmaeil

Abstract excerpt

Cystic fibrosis (CF) is the most common lethal autosomal recessive disease in white Caucasians. It affects many organs including the lung, pancreas, and liver. Whilst CF is a monogenic disease, several studies revealed a complex relationship between genotype and clinical phenotype of diseases. We examined the expression of human leukocyte antigen (HLA) class II alleles among Iranian CF patients with...

Topics

Alleles
Cystic Fibrosis
Female
HLA-DRB1 Chains
Humans
Immunoglobulin E
Iran
Male

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Open in PubMed

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PMID: 35490272
DOI: 10.18502/ijaai.v21i2.9226

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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