Article
HLA-DRB1 and HLA-DQB1 genes on susceptibility to and protection from allergic bronchopulmonary aspergillosis in patients with cystic fibrosis.
Microbiology and immunology - 1 Mar 2013
Muro Manuel, Mondejar-López Pedro, Moya-Quiles María Rosa, Salgado Gema, Pastor-Vivero María Dolores, Lopez-Hernandez Ruth, Boix Francisco, Campillo José Antonio, Minguela Alfredo, Garcia-Alonso Ana, Sánchez-Solís Manuel, Álvarez-López María Rocío
Abstract excerpt
Allergic bronchopulmonary aspergillosis (ABPA) is a hypersensitivity pulmonary disease that affects both patients with cystic fibrosis (CF) and those with asthma. HLA-DRB1 alleles have previously been associated with ABPA-CF susceptibility; however, HLA-DQB1 allele associations have not been clearly established. The aim of the present study was to investigate HLA class II associations in patients with ABPA-CF and...
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