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Article

HLA class II polymorphism in cystic fibrosis. A possible modifier of pulmonary phenotype.

American journal of respiratory and critical care medicine - 1 May 1999

Aron Y, Polla B S, Bienvenu T, Dall'ava J, Dusser D, Hubert D

Abstract excerpt

Evolution of lung damage is highly variable in cystic fibrosis (CF) even in patients with the same cystic fibrosis transmembrane conductance regulator (CFTR) mutations. The analysis of genetic factors other than CFTR may help our understanding of genotype-phenotype relationships in CF. As human leukocyte antigen (HLA) class II polymorphism has been associated with a number of diseases including autoimmune and...

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Source

Identifiers

PMID: 10228112
DOI: 10.1164/ajrccm.159.5.9807046

Genes

CFTR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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