Article
HLA frequencies and associations in cystic fibrosis.
Tissue antigens - 1 Jan 2014
Adriaanse M P M, Vreugdenhil A C E, Groeneweg M, Brüggenwirth H T, Castelijns S J A M, van der Ent C K, Voorter C E M, Tilanus M G J
Abstract excerpt
Cystic fibrosis (CF) is classically attributed to the dysfunction of the single CF transmembrane conductance regulator gene. The incidence of human leukocyte antigen (HLA) polymorphisms in different CF-associated diseases raises the question of an unequal distribution of HLA genotypes in CF. This study aimed to evaluate HLA gene frequencies and possible associations in CF patients compared with a control...
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