Article
CFTR haplotypes in northern Iranian population.
Gene - 1 Jan 2013
Kholghi Oskooei Vahid, Esmaeili Dooki Mohammad Reza, Tabaripour Reza, Mirzajani Sara, Pourbagher Roghieh, Akhavan-Niaki Haleh
Abstract excerpt
BACKGROUND: Cystic fibrosis (CF) is a multiorganic autosomal recessive disorder, caused by mutation in cystic fibrosis transmembrane conductance regulator (CFTR). CF is highly heterogeneous in Iranian population and molecular diagnosis based on direct identification of mutations is not completely efficient. The use of polymorphic intragenic markers not only can facilitate phenotype prediction in prenatal...
Topics
- Adolescent
- Adult
- Alleles
- Child
- Child, Preschool
- Codon
- Cystic Fibrosis
- Cystic Fibrosis Transmembrane Conductance Regulator
- Female
- Haplotypes
- Humans
- Infant