Article
A review ofimaging genetics in Alzheimer's disease.
Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia - 1 Jun 2022
Xin Yu, Sheng Jinhua, Miao Miao, Wang Luyun, Yang Ze, Huang He
Abstract excerpt
Determining the association between genetic variation and phenotype is a key step to study the mechanism of Alzheimer's disease (AD), laying the foundation for studying drug therapies and biomarkers. AD is the most common type of dementia in the aged population. At present, three early-onset AD genes (APP, PSEN1, PSEN2) and one late-onset AD susceptibility gene apolipoprotein E (APOE) have been determined....
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