Article
Transcriptome-guided amyloid imaging genetic analysis via a novel structured sparse learning algorithm.
Bioinformatics (Oxford, England) - 1 Sept 2014
Yan Jingwen, Du Lei, Kim Sungeun, Risacher Shannon L, Huang Heng, Moore Jason H, Saykin Andrew J, Shen Li
Abstract excerpt
MOTIVATION: Imaging genetics is an emerging field that studies the influence of genetic variation on brain structure and function. The major task is to examine the association between genetic markers such as single-nucleotide polymorphisms (SNPs) and quantitative traits (QTs) extracted from neuroimaging data. The complexity of these datasets has presented critical bioinformatics challenges that require new...
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