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Article

Detecting genetic associations with brain imaging phenotypes in Alzheimer's disease via a novel structured KCCA approach.

Journal of bioinformatics and computational biology - 1 Aug 2021

Wang Lei, Kong Wei, Wang Shuaiqun

Abstract excerpt

Neuroimaging genetics has become an important research topic since it can reveal complex associations between genetic variants (i.e. single nucleotide polymorphisms (SNPs) and the structures or functions of the human brain. However, existing kernel mapping is difficult to directly use the sparse representation method in the kernel feature space, which makes it difficult for most existing sparse canonical...

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PMID: 33950804
DOI: 10.1142/S0219720021500128

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