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Article

AT2R activation increases in vitro angiogenesis in pregnant human uterine artery endothelial cells

29 Apr 2022

Abstract excerpt

Angiogenesis is vital during pregnancy for remodeling and enhancing vasodilation of maternal uterine arteries, and increasing uterine blood flow. Abnormal angiogenesis is associated with decreased uteroplacental blood flow and development of pregnancy disorders such as gestational hypertension, preeclampsia, fetal growth restriction, preterm delivery, stillbirth, and miscarriage. The mechanisms that contribute to...

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PMID: 35486619
DOI: 10.1371/journal.pone.0267826

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