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Orphan nuclear receptors in angiogenesis and follicular development

16 Jul 2021

Abstract excerpt

Orphan nuclear receptors (ONRs) are a subset of the nuclear receptor family that lacks known endogenous ligands. Among 48 nuclear receptors identified in humans, 25 are classified as ONRs. They function as transcription factors and control the expression of a wide range of genes to regulate metabolism, fertility, immunity, angiogenesis, and many other functions. Angiogenic factors are essential during ovarian...

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PMID: 34270446
DOI: 10.1530/rep-21-0118

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