Article
Intrauterine growth restriction neonates present with increased angiogenesis through the Notch1 signaling pathway.
Microvascular research - 1 Mar 2022
Li Min, Zhang Zhiqun, Joynauth Jyotsnav, Zhan Xueqin, Du Lizhong
Abstract excerpt
Intrauterine growth restriction (IUGR) is associated with increased perinatal mortality and morbidity, and plays an important role in the development of adult cardiovascular diseases. This study brings forward a hypothesis that Human umbilical vein endothelial cells (HUVECs) from IUGR newborns present dysfunctions and varying changes of signaling pathways as compared to the Control group. Similar pathways may...
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