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Article

Does the Renin-Angiotensin System Participate in Regulation of Human Vasculogenesis and Angiogenesis?

14 Nov 2008

Abstract excerpt

Several lines of evidence suggest that hypertension and angiogenesis may be related phenomena but a functional link remains elusive. Here, we propose that the renin-angiotensin system (RAS), in addition to its central role in arterial hypertension, also regulates blood vessel formation during normal development and cancer. This mechanistic hypothesis is based on reports of biochemical, genetic, clinical, and...

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PMID: 19010879
DOI: 10.1158/0008-5472.can-08-0851

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