Article
Pre- and Post-operative Circulating Tumoral DNA in Patients With Medullary Thyroid Carcinoma.
The Journal of clinical endocrinology and metabolism - 14 Jul 2022
Ciampi Raffaele, Romei Cristina, Ramone Teresa, Matrone Antonio, Prete Alessandro, Gambale Carla, Materazzi Gabriele, De Napoli Luigi, Torregrossa Liborio, Basolo Fulvio, Castagna Maria Grazia, Brilli Lucia, Ferretti Elisabetta, Elisei Rossella
Abstract excerpt
CONTEXT: Measurement of driver mutations in circulating tumoral DNA (ctDNA) obtained by liquid biopsy has been shown to be a sensitive biomarker in several human tumors. OBJECTIVE: The aim of this study was to evaluate the clinical relevance of pre- and post-operative ctDNA in sporadic medullary thyroid cancer (sMTC). METHODS: We studied pre- and post-operative ctDNA in 26 and 23 sMTC patients, respectively....
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