Article
Circulating Biomarkers in Medullary Thyroid Carcinoma: Assays, Clinical Performance, and Integrated Algorithms
2025-07-08
Abstract excerpt
Medullary thyroid carcinoma (MTC) is a rare neuroendocrine tumor arising from parafollicular C-cells, accounting for 2-5% of thyroid cancers. Effective management relies on circulating biomarkers for diagnosis, staging, and post-operative monitoring. Calcitonin (CT) remains the gold standard biomarker, demonstrating high sensitivity and specificity for MTC detection. However, CT measurement faces analytical challe...
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Identifiers and source
- Literature Corpus work
- eaa39a51-9faa-58e0-ac1a-b74816c5afec
- DOI
- 10.20944/preprints202507.0704.v1