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Article

Autophagy in age-related macular degeneration

25 Apr 2022

Abstract excerpt

Age-related macular degeneration (AMD) is the leading cause of visual impairment in the aging population with limited understanding of its pathogenesis and a lack of effective treatment. The progression of AMD is initially characterized by atrophic alterations in the retinal pigment epithelium, as well as the formation of lysosomal lipofuscin and extracellular drusen deposits. Damage caused by chronic oxidative...

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PMID: 35468037
DOI: 10.1080/15548627.2022.2069437

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